A Method to Map Brain Circuits in Real Time
10-16-20
A new approach called integrated neurophotonics could allow researchers to track the activity of all the neurons that make up a particular brain circuit. To deepen their understanding of the brain, neuroscientists must be able to map in great detail the neural circuits that are responsible for tasks such as processing sensory information or forming new memories. Now, a new approach may allow for the activity of all of the thousands to millions of neurons within a particular brain circuit to be observed in real time. Dense recording at depth—that is the key," says Michael Roukes, Frank J. Roshek Professor of Physics, Applied Physics, and Bioengineering. [Caltech story]
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Michael Roukes
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Seeking a Balanced Equation
03-21-16
Applied Physics graduate student Peter Hung, working with Professor Roukes, is one of the Caltech students featured in a recent E&S article. “In our lab, we shoot molecules of different sizes and shapes at really small mechanical resonators—tiny bridges almost 1,000 times smaller than the width of your hair—and use the change in the resonant frequency (how fast these bridges are vibrating) to reconstruct the shape and mass of the molecules that we’re shooting,” Hung explains. [E&S article]
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Professor Roukes Honored by the French Republic
06-28-13
Michael L. Roukes, Robert M. Abbey Professor of Physics, Applied Physics, and Bioengineering, has received the Chevalier de l'ordre des Palmes Académiques, which is the Knight grade of the French Republic's Order of Academic Palms. Founded by Napoleon in 1808 to honor educators and scholars, this distinction recognizes eminent personalities who have made significant contributions to the development of French culture, science, and education. The Consul General of France in Los Angeles, Axel Cruau, presented Professor Roukes with the medal and in his remarks he cited Roukes's collaborations with French research institutions and noted his instrumental role in helping to start the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, a national program proposed by President Barack Obama to build a comprehensive map of activity in the human brain. [Caltech Release]
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Michael Roukes
Order of Academic Palms
Accelerating Nanoscience out of the Laboratory and into the Marketplace
12-13-11
The Alliance for Nanosystems VLSI (very-large-scale-integration)—a collaboration between the Kavli Nanoscience Institute and Leti-Minatec in France—has launched its first start-up company. The Alliance, which began informally in 2005, was officially created in 2007 to transform academic, nanotechnology-based prototypes into robust, complex sensing systems and thus accelerate nanoscience out of the laboratory and into the marketplace. The start-up company, Analytical Pixels, will focus on the design, manufacture, and commercialization of multi-gas sensing systems created over the past five years in the field of nanoelectromechanical devices, read-out electronics, and system integration, and built on two decades of prior research carried out at Caltech. [Caltech Feature]
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Oskar Painter
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Michael Roukes and Akshay Naik Create First Nanoscale Mass Spectrometer
07-22-09
Michael L. Roukes, Professor of Physics, Applied Physics, and Bioengineering; Co-Director, Kavli Nanoscience Institute, and colleague Akshay Naik have created the first nanoscale mass spectrometer. This new technique simplifies and miniaturizes the measurement of the mass of molecules through the use of very tiny nanoelectromechanical system (NEMS) resonators. Askshay Naik explains, "the frequency at which the resonator vibrates is directly proportional to its mass. When a protein lands on the resonator, it causes a decrease in the frequency at which the resonator vibrates and the frequency shift is proportional to the mass of the protein." Professor Roukes points out, "the next generation of instrumentation for the life sciences must enable proteomic analysis with very high throughput. The potential power of our approach is that it is based on semiconductor microelectronics fabrication, which has allowed creation of perhaps mankind's most complex technology." [Caltech Press Release]
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