Microstructures Self-Assemble into New Materials
A new process developed at Caltech makes it possible for the first time to manufacture large quantities of materials whose structure is designed at a nanometer scale—the size of DNA's double helix. Pioneered by Julia R. Greer, Ruben F. and Donna Mettler Professor of Materials Science, Mechanics and Medical Engineering; Fletcher Jones Foundation Director of the Kavli Nanoscience Institute, "nanoarchitected materials" exhibit unusual, often surprising properties—for example, exceptionally lightweight ceramics that spring back to their original shape, like a sponge, after being compressed. Now, a team of engineers at Caltech and ETH Zurich have developed a material that is designed at the nanoscale but assembles itself—with no need for the precision laser assembly. "We couldn't 3-D print this much nanoarchitected material even in a month; instead we're able to grow it in a matter of hours," says Carlos M. Portela, Postdoctoral Scholar. "It is exciting to see our computationally designed optimal nanoscale architectures being realized experimentally in the lab," says Dennis M. Kochmann, Visiting Associate. [Caltech story]
Solving Pieces of the Genetic Puzzle
Postdoctoral scholar Nathan Belliveau working in the laboratory of Professor Rob Phillips has applied a method called Sort-Seq to mutate small pieces of noncoding regions in E. coli and determined which regions contain binding sites. Binding sites are the locations where specialized proteins that are involved in transcription—the first step in the process of gene expression—attach to DNA. "Humans have such a wide variety of cells—muscle cells, neurons, photoreceptors, blood cells, to name a few," says Professor Phillips. "They all have the same DNA, so how do they each turn out so differently? The answer lies in the fact that genes can be regulated—turned on or off, dialed up and dialed down—differently in different tissues. Until now, there have been no general principles to help us understand how this regulation was encoded." [Caltech story]
Former Caltech Postdoc Receives Israel Prize
Mordechai (Moti) Segev, a former postdoctoral fellow in Professor Amnon Yariv's group, will be receiving the Israel Prize for Physics and Chemistry. Dr. Segev is receiving the prize for ground-breaking research in the field of optics and lasers. "I am naturally proud of the achievements of former students and postdocs who started their scientific career in my group," says Professor Yariv. "Among this group Moti has become, in the relatively short time since leaving us, one the best known and influential scientists in the world in the field of quantum electronics and its amazing offspring of nonlinear optics. I am looking forward to a continuing stream of intellectual and experimental innovation flowing from him and his research group at the Technion."